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The Revolution Plus Difference

Combining the power of selamectin and sarolaner, Revolution Plus protects against 6 of the most common parasites with a unique dual action against fleas and ear mites.2

Select One of the Most Common Feline Parasites Below to Learn More
Flea Icon Flea Icon Flea Icon

FLEAS

The dual action of Revolution Plus (sarolaner and selamectin) was highly effective against fleas.4,5

  • Revolution Plus is indicated for the treatment and prevention of flea infestations2

  • Revolution Plus kills fleas before they lay eggs and for a full 5 weeks2

  • Unlike some other broad-spectrum protection products, Revolution Plus starts killing fleas within 6 hours,2 with complete flea protection at 24 hours6

  • 100% reduction in adult flea count for at least 35 days in TWO clinical trials against an existing infestation and weekly reinfestation2

  • Decreases signs of flea allergy dermatitis2

  • Kills fleas that may spread tapeworms7

Today, Revolution Plus is veterinarians' #1 prescribed parasiticide for cats.1

TICKS

  • Kills ticks for a full month8,9

  • Tick-killing efficacy for up to 5 weeks for black-legged or deer tick and American dog tick8,10

  • The only feline isoxazoline combination formula that protects against Amblyomma maculatum ticks

Black-legged or Deer Tick

(Ixodes scapularis)

Gulf Coast Tick

(Amblyomma maculatum) 

American Dog Tick

(Dermacentor variabilis) 

Photos: James Gathany, Centers for Disease Control and Prevention

EAR MITES

Revolution Plus is highly effective against ear mites.

Did You Know?

Cats can have more than 1,000 ear mites per ear.11

Revolution Plus offers dual action against ear mites, helping keep your feline patients comfortable and protected.

ROUNDWORMS AND HOOKWORMS

  • Revolution Plus is highly effective against roundworms and hookworms

  • Nearly 100% reduction in roundworm (Toxocara cati) fecal egg count on Days 30 and 60 (dosed once monthly)12

  • 99.4% reduction in hookworm (Ancylostoma tubaeforme) fecal egg counts at 30 days and 99.7% at 60 days12

HEARTWORMS

  • 100% effective in preventing heartworm disease caused by Dirofilaria immitis, in two clinical studies2

  • In studies, Revolution Plus provided 100% heartworm protection with a SINGLE dose2

Do Your Clients Know?

Juvenile worms in cats can cause severe lung damage, known as heartworm-associated respiratory disease (HARD),13 and sudden death.

Although adult heartworm infections are less common (10% the rate of dogs), immature infections can cause HARD.13

Reasons You Love Revolution Plus

Reason #915

Because Trusted Parasite Protection Is Only a Few Clicks Away

Reasons You Love Revolution Plus

Reason #915

Because Trusted Parasite Protection Is Only a Few Clicks Away
Order Now

References:

  1. Data on file. Zoetis Inc.
  2. Revolution Plus (selamectin and sarolaner topical solution). Package insert. Zoetis Inc; 2023.
  3. Indoor Cats Parasiticides Tracker: “Stock Up” survey; fielded on 5/21-6/5/2018. Data on file. Zoetis Inc.
  4. Dryden MW, Canfield MS, Bocon C, et al. In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA. Parasit Vectors. 2018;11(1):422. doi:10.1186/s13071-018-2995-1
  5. Dryden MW, Herrin BH, Canfield MS, et al. Evaluation of a topical sarolaner-selamectin combination to control flea populations on naturally infested cats in private residences in West Central Florida. Vet Parasitol. 2020;283:109172. doi:10.1016/j.vetpar.2020.109172
  6. Study Report No. A186C-US-14-108. Data on file. Zoetis, Inc. 2014.
  7. Dipylidium caninum. Companion Animal Parasite Council. Updated November 22, 2022. Accessed May 3, 2023. https://capcvet.org/guidelines/dipylidium-caninum/
  8. Study Report No. A186C-US-14-100. Data on file. Zoetis, Inc. 2014.
  9. Study Report No. A186C-US-14-106. Data on file. Zoetis, Inc. 2014.
  10. Study Report No. A186C-US-14-098. Data on file. Zoetis, Inc. 2014.
  11. Otodectic mite. Companion Animal Parasite Council. Updated March 13, 2019. Accessed May 3, 2023. https://capcvet.org/guidelines/otodectic-mite/
  12. Study Report No. A186C-US-14-166. Data on file. Zoetis, Inc. 2017.
  13. Heartworm. Companion Animal Parasite Council. Updated July 28, 2020. Accessed September 23, 2022. https://capcvet.org/guidelines/heartworm/
  14. NexGard COMBO Package insert. Boehringer Ingelheim; 2023.
  15. Regions where ticks live. Centers for Disease Control and Prevention. Updated December 5, 2022. Accessed February 10, 2023. https://www.cdc.gov/ticks/geographic_distribution.html
  16. Ticks. Companion Animal Parasite Council. Updated April 12, 2017. Accessed February 10, 2023. https://www.capcvet.org/guidelines/ticks/
  17. Tick-borne diseases reported in most states, expert says. Companion Animal Parasite Council. Accessed February 10, 2023. https://capcvet.org/articles/tick-borne-diseases-reported-in-most-states-expert-says/

RVP-00610

IMPORTANT SAFETY INFORMATION

See full Prescribing Information. The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Sarolaner, one of the ingredients in Revolution Plus, is a member of the isoxazoline class, which has been associated with adverse reactions such as tremors, ataxia, and seizures. Reactions have occurred in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information.

Revolution Plus is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. Revolution Plus kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations with Ixodes scapularis (black-legged tick), Amblyomma maculatum (Gulf Coast tick) and Dermacentor variabilis (American dog tick), the treatment and control of ear mite (Otodectes cynotis) infestations, and the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections for one month in cats and kittens 8 weeks and older, and weighing 2.8 pounds or greater.

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IMPORTANT SAFETY INFORMATION

See full Prescribing Information. The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Sarolaner, one of the ingredients in Revolution Plus, is a member of the isoxazoline class, which has been associated with adverse reactions such as tremors, ataxia, and seizures. Reactions have occurred in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information.

Revolution Plus is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. Revolution Plus kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations with Ixodes scapularis (black-legged tick), Amblyomma maculatum (Gulf Coast tick) and Dermacentor variabilis (American dog tick), the treatment and control of ear mite (Otodectes cynotis) infestations, and the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections for one month in cats and kittens 8 weeks and older, and weighing 2.8 pounds or greater.